Honestly, it comes down to how much power you really need. With a 0-60 of 6.5 seconds, the V6 is probably fast enough for most people, and Mercedes expects roughly 75% will opt for this choice. Luckily, most options available on the V8 can be had on the V6, though the V8 comes with an upgraded Airmatic suspension which allows for a greater degree of control between comfort and sport ride quality. All engines route power through a super-smooth standard 7-speed transmission which makes for a quicker and more fuel-efficient car (it's always nice when technology doesn't demand those two to be mutually exclusive).